Table 2. DNA methylation in different cell lines and UROtsa stocks.
Gene promoter region (% methylation) | |||||||||||
Cell line | LINE1 | RARB | PGR | RASSF1 | CDH1 | FHIT | ERS1 | C1QTNF6 | PTGS2 | SOCS3 | MGMT |
UROtsa- 4 | 56 | 96 | 11 | 1 | 2 | 5 | 15 | 12 | 2 | 1 | 1 |
UROtsa-3 (A) | 46 | 64 | 89 | 91 | 23 | 41 | 42 | 9 | 2 | 3 | 4 |
UROtsa-3 (B) | 50 | 57 | 93 | 91 | 22 | 36 | 30 | 8 | 4 | 2 | 3 |
UROtsa/F35 | 52 | 66 | 93 | 84 | 23 | 44 | 38 | 28 | 3 | 3 | 1 |
T24 (ACC 376) | 47 | 50 | 95 | 93 | 83 | 48 | 86 | 18 | 2 | 1 | 1 |
HeLa S3 (CCL-2.2) | 69 | 98 | 91 | 3 | 97 | 87 | 98 | 7 | 3 | 43 | 2 |
HepG2 (HB-8065) | 54 | 5 | 88 | 89 | 7 | 3 | 5 | 31 | 72 | 79 | 62 |
RT4 (ACC 412) | 60 | 18 | 74 | 51 | 4 | 4 | 5 | 9 | 3 | 73 | 2 |
BEAS-2B (CRL-9609) | 57 | 10 | 40 | 2 | 8 | 5 | 14 | 11 | 6 | 2 | 7 |
Urothel urine* | 69 | 2 | 9 | 2 | 3 | 2 | 1 | 18 | 4 | 1 | 2 |
HUEPC | 56 | 2 | 3 | 1 | 1 | 2 | 2 | 8 | 1 | 2 | 1 |
Mean of results obtained from four different healthy persons.