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. 2013 May 17;8(5):e63331. doi: 10.1371/journal.pone.0063331

Figure 3. Progression of M.tb infection in humanized BLT mice.

Figure 3

Animals were infected i.n. with CFU tdTomato H37RV M.tb and in-vivo imaging (IVIS) performed at weekly time points. Shown in A is the fluorescent intensity signal from a group of animals infected with 106 CFU represented with a pseudocolor scale ranging from yellow (most intense) to dark red (least intense) and IVIS images of BLT mice; across: non-infected control mouse and M.tb infected BLT mice at 1, 2, and 4 weeks p.i. B, bacterial burden (CFU) are shown per milligram (mg) of tissue from individual animals (n = 3 per time point) at 2, 3, and 4 weeks p.i.