Figure 6. PDBu-induced cytokines were selectively regulated by different PKC sub-class isozymes.

(A) G-CSF was inhibited by pan or classical PKC inhibitors. (B) IL-7 and GRO-1α were inhibited by pan PKC or novel PKC inhibitors. (C) IFNα2 and IL-6 are inhibited by pan, classical PKC or novel PKC inhibitors. (D) Fractalkine and IL-8 are inhibited only by pan PKC inhibitors. (E) The table summarizes the selective regulation of cytokines by different PKC subclass isozymes.