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. 2013 May 17;8(5):e64182. doi: 10.1371/journal.pone.0064182

Figure 7. PKCα and PKCδ siRNA were utilized to confirm the inhibitor results.

Figure 7

(A) The protein expressions of PKCα and PKCδ were specifically downregulated by their respective siRNAs. (B) PKCδ, but not PKCα siRNA, was able to inhibit the GRO-1α production. (C) Both PKCδ and PKCα siRNA inhibited the IL-6 production. (D) Neither PKCδ siRNA nor PKCα siRNA were able to inhibit the IL-8 production. (E) PKCα siRNA did not reduce the G-CSF production, suggesting that classical PKCs other than PKCα regulate the production of G-CSF.