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A patient with a 2.2 cm invasive breast cancer was imaged with MBI prior to initiation of neoadjuvant chemotherapy (panel a) and again at 3 weeks after initiation (panel b). MBI performed at 3 weeks showed nearly complete resolution of the tumor, indicating a functional response to neoadjuvant chemotherapy. Surgery performed after four months of therapy showed complete pathological response (pCR), i.e., no residual in situ or invasive disease.
