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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: J Thromb Haemost. 2013 May;11(5):911–918. doi: 10.1111/jth.12188

Fig. 1.

Fig. 1

CHO-TF and CHO-TF/TFPIβ cells have similar TF expression and activity. (A) Flow cytometry for TF on CHO-TF (filled dark grey) and CHO-TF/TFPIβ cells (solid line) and for TFPI on CHO-TF/TFPIβ cells (dotted line). The isotype control is shaded light grey. The data are representative of 3 experiments. (B) TF-FVIIa-mediated FXa generation on CHO-TF cells and CHO-TF/TFPIβ cells. TFPIβ decreases the amount of FXa generated (p<0.001) and can be totally reversed by anti-TFPI polyclonal antibody or by treatment of the cells with PIPLC (mean ± SEM, n=3).