Table 1.
Group | N | Survival (%) | P | |
---|---|---|---|---|
1 | No treatment | 20 | 7 (35) | Reference |
2 | FVIII alone | 17 | 15 (88.2) | 0.001 |
3 | FVIII + anti-IL-6R | 15 | 15 (100) | <0.001 |
4 | FVIII + control IgG | 10 | 9 (90) | 0.008 |
5 | Anti-IL-6R alone | 20 | 8 (40) | 0.492 |
6 | Injured WT | 10 | 10 (100) | 0.002 |
Survival rate was evaluated on day 42 following the first injury. P values for significant difference compared to the “No treatment” group were calculated using log-rank test.