Fig. 3.
(a) Initial (Left) and one of the evolved (Right) conformations. The evolved conformation is not maximally compact but has much greater higherorder normalized contact traces: TrC4/36 = 4.72(4.0), TrC6/36 = 34.79(16.39), and TrC8/36 = 234.2(62.3) (the numbers in parentheses correspond to starting structure shown in Left). (b) Designability: number of sequences that fit initial (diamonds) and one of the evolved (circles) structures with or below a given energy. The details of the calculation are given in Methods.
