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. 2013 Jan 13;32(6):745–754. doi: 10.1007/s10096-012-1799-z

Table 4.

Impact of IL-28B SNP on high baseline viral load according to 600,000 and 800,000 IU/ml stratification

Baseline viral load (IU/ml) IL-28B SNP OR (95 % CI) p-Value
CC rs12979860 CT–TT rs12979860
≥600,000 12 (37.5 %) 20 (62.5 %) 5.40 (1.68–17.38) 0.003
<600,000 5 (10.0 %) 45 (90.0 %)
≥800,000 5 (26.3 %) 14 (73.7 %) 1.52 (0.46–5.04) 0.493
<800,000 12 (19.0 %) 51 (81.0 %)
TT rs8099917 TG–GG rs8099917
≥600,000 18 (56.2 %) 14 (43.8 %) 2.50 (1.00–6.21) 0.047
<600,000 17 (34.0 %) 33 (66.0 %)
≥800,000 9 (47.4 %) 10 (52.6 %) 1.28 (0.46–3.59) 0.638
<800,000 26 (41.3 %) 37 (58.7 %)
AA rs12980275 AG–GG rs12980275
≥600,000 10 (31.2 %) 22 (68.8 %) 3.33 (1.07–10.36) 0.032
<600,000 6 (12.0 %) 44 (88.0 %)
≥800,000 5 (26.3 %) 11 (17.5 %) 1.69 (0.50–5.67) 0.509
<800,000 14 (73.7 %) 52 (82.5 %)

CI confidence interval; OR odds ratio