Fig. 2.

Abnormal development in Hpr mice scapula: Plots (top row—left to right) show the 3D rendered images from micro-CT and their 2D composite maps combining predominant orientation (direction of the lines) and degree (black = high degree of alignment, white = low degree of alignment and lengths of the lines) of mineral nanocrystallite orientation in normal mice. Plots (bottom row left to right) show the same for Hpr mice. In both cases, surface porosity decreases with age, but less pronounced in Hpr. The overall degree of orientation, as indicated by the greyscale and lengths of the lines, increases with age. However while the degree of orientation in wild-type mice increases at the bony ridges at the edge of the scapulae, in Hpr mice the increment is not to the same extent.