Table 2.
Dominant hand | 95% CI | Non-dominant hand | 95% CI | P value | |
---|---|---|---|---|---|
Mean score FDIO | 3.78 | 3.56, 4.00 | 4.00 | 3.80, 4.00 | <0.0001 |
Mean score APB | 3.38 | 3.02, 3.75 | 3.69 | 3.35, 4.02 | 0.0001 |
CMAP median (APB, mV) | 2.03 | 0.96, 3.10 | 3.03 | 2.13, 3.93 | 0.02 |
CMAP ulnar (ADM, mV) | 4.70 | 3.15, 6.25 | 4.86 | 3.48, 6.24 | 0.89 |
Patients with CMT1X have a higher mean MRC strength score for the first dorsal interosseous (FDIO) muscle and the abductor pollicis brevis (APB) muscle in non-dominant hands compared to dominant hands. Median nerve compound motor action potentials (CMAP) (measured on APB) were larger in non-dominant hands whereas ulnar nerve CMAPs (measured on abductor digiti minimi, ADM) were similar between hands. Mean values with 95% confidence interval are shown.