Fig. 1.

Primary cilia disassembly prior to mitosis. The primary cilium present in G0/G1 phase starts to disassemble at G1-S transition, and is completely resorbed at early prophase. In some descriptions of quiescent cultured cells stimulated to reenter cell cycle by administration of serum, the primary cilium reassembles after disassembly at G1-S and is present during DNA and centriole duplication at S phase, and centriole maturation at G2 phase. Other reports describe two waves of deciliation, with some cells losing cilia prior to G1/S transition and the remainder losing cilia at the end of G2 phase