Table 1. HuR motif-bearing targets on cDNA arrays.
| Motif position and score | Accession no. | Gene |
|---|---|---|
| 969 (3.42) | Hs#S3322070 | Matrix metalloprotease 7 (MMP7) |
| 1714 (1.42), 1783 (0.78) | Hs#S1726209 | Actin, gamma 1 (ACTG1) |
| 537 (1.00), 750 (0.42) | NM_004181.3 | Ubiquitin thiolesterase (UCHL1) |
| 1434 (2.00), 1492 (2.42), 1515 (1.42) | Hs#S5494967 | Sorting nexin 3 (SNX3), transcript variant 3 |
| 571 (0.42), 929 (0.29), 977 (0.42) | Hs#S1727443 | Protein phosphatase 1, catalytic subunit β (PPP1CB) |
| 1417 (0.36), 1610 (1.83), 2332 (2.42) | ||
| 2414 (0.83), 2707 (0.42), 3423 (4.00) | ||
| 3439 (4.00), 3515 (0.01) | ||
| 2824 (0.42) | Hs#S1729935 | Solute carrier family 1 (SLC1A5) |
| 3848 (1.71), 1184 (0.42) | Hs#S1728144 | Ubiquitin-conjugating enzyme E2N (UBE2N) |
| 436 (0.42), 2470 (2.38) | Hs#S1729115 | Metastasis-associated 1 (MTA1) |
| 3845 (0.29) | Hs#S1824446 | Leucine zipper-EF-hand transmembrane (LETM1) |
| 2320 (1.42) | Hs#S1730282 | Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) |
| 496 (1.36), 626 (0.42), 734 (0.01) | Hs#S1727788 | Chemokine (C-X-C motif) ligand 6 (CXCL6) |
| 789 (0.29), 1311 (0.42) | ||
| 1263 (0.29), 2039 (3.42), 3111 (1.42) | Hs#S1731058 | Poliovirus receptor (PVR) |
| 2876 (0.83), 3288 (0.42), 3533 (0.01), 3564 (0.42), 3727 (0.42), 3958 (1.42), 4032 (1.42), 4078 (0.42), 4310 (2.00), 4340 (0.29), 4497 (1.88), 4566 (0.42) | Hs#S2294124 | Minichromosome maintenance deficient 10 (MCM10) |
| 791 (1.42) | Hs#S1731210 | Ribosomal protein L14 (RPL14) |
| 768 (2.65), 797 (0.88), 1031 (0.83), 1103 (0.42) | Hs#S1727552 | Prothymosin, alpha (PTMA) |
| 1102 (1.42), 1210 (0.29), 1235 (0.01) | Hs#S3438634 | RNA processing factor 1 (RPF1) |
| 1934 (1.29), 3085 (0.42), 3323 (0.01), 3359 (2.42), 3622 (1.42) | Hs#S1731856 | Karyopherin alpha 4 (importin alpha 3) (KPNA4) |
| 724 (0.42), 2028 (0.83) | Hs#S4631077 | Crystallin, zeta (quinone reductase)-like 1 (CRYZL1) |
| 580 (4.00), 828 (0.42), 985 (1.42) | Hs#S1731044 | RNA polymerase II transcription cofactor 4 (PC4) |
| 691 (3.29), 1519 (0.29) | NM_000801.2 | FK506 binding protein 1A, 12 kDa (FKBP1A) |
Partial list of genes encoding transcripts more abundantly found in HuR immunoprecipitates; these were used to create the experimental data set and derive the HuR motif. The relative position(s) of the HuR motif within each transcript and the corresponding scores (parentheses, bold) are indicated. A complete list of transcripts enriched in HuR IP compared with IgG1 IP is available as supporting information on the PNAS web site.