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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Am J Cardiol. 2013 Mar 15;111(11):1541–1546. doi: 10.1016/j.amjcard.2013.02.003

Table 4.

Comparison of hazards ratios from competing models* with standard Cox regression models by CAC in men and women

Event Type Hazards ratios in Men Hazards ratios in Women
Stroke CAC Cox regression Fine and Gray Cox regression Fine and Gray
0 1.0 (ref) 1.0 (ref) 1.0 (ref) 1.0 (ref)
1–99 1.81 (0.92,3.56) 1.53 (0.78,2.99) 1.60 (0.88,2.93) 1.52 (0.82,2.82)
≥ 100 1.77 (0.89,3.51) 1.59 (0.84,3.02) 1.71 (0.88,3.30) 1.59 (0.79,3.22)
CHD/NFMI 0 1.0 (ref) 1.0 (ref) 1.0 (ref) 1.0 (ref)
1–99 2.71 (1.65,4.46) 2.92 (1.75,4.87) 1.87 (1.12,3.11) 1.97 (1.17,3.33)
> 100 5.81 (3.61,9.37) 6.31 (3.82,10.4) 4.20 (2.52, 7.00) 4.25 (2.44, 7.40)
Any CVD event 0 1.0 (ref) 1.0 (ref) 1.0 (ref) 1.0 (ref)
1–99 2.02 (1.40,2.91) 1.99 (1.38,2.87) 1.64 (1.13,2.37) 1.63 (1.12,2.38)
≥ 100 3.68 (2.59, 5.23) 3.65 (2.55, 5.22) 3.20 (2.20,4.66) 3.18 (2.14,4.72)
Non-CVD death 0 1.0 (ref) 1.0 (ref) 1.0 (ref) 1.0 (ref)
1–99 1.35 (0.87,2.09) 1.22 (0.78,1.88) 1.20 (0.76, 1.87) 1.16 (0.73, 1.82)
≥ 100 1.46 (0.95,2.24) 1.15 (0.75,1.76) 1.25 (0.77,2.05) 1.07 0.64,1.78)
*

denotes that hazards ratios from competing model obtained using the method of Fine and Gray

All hazards ratios adjusted for age, race, systolic blood pressure, total and HDL cholesterol, smoking status, and diabetes

CAC = coronary artery calcium; CHD/NFMI = coronary heart disease/nonfatal myocardial infarction; CVD = cardiovascular disease