Table 4. Longitudinal Changes in Symptoms and QOL By Disease Stage.

Psychological distress
Distress thermometer
I & II	3.49	2.78	3.49	2.65	3.53	2.9	3.28	2.85	3.55	2.8	3.51	2.56	0.693	0.577
III	3.94	2.47	4.31	2.3	3.43	2.5	4.17	2.68	4.2	2.7	4.29	2.8
Total	3.68	2.65	3.84	2.53	3.49	2.72	3.66	2.8	3.83	2.76	3.84	2.68
Symptoms
Memorial Syr0nptoms Assessment Scale (global distress index)
I & II	1.42	0.77	1.42	0.72	1.31	0.74	1.28	0.72	1.18	0.74	1.24	0.77	0.053	0.559
III	1.56	0.77	1.46	0.63	1.51	0.72	1.45	0.79	1.45	0.72	1.26	0.79
Total	1.48	0.77	1.44	0.68	1.4	0.73	1.36	0.76	1.3	0.74	1.25	0.78
Memorial Symptoms Assessment Scale (physical symptom subscale)
I & II	1.66	0.93	1.88	0.93	1.69	0.82	1.75	0.91	1.76	0.8	1.85	0.56	0.658	0.22
III	1.75	0.84	1.59	0.74	1.77	0.73	1.74	0.77	1.92	0.76	1.79	0.63
Total	1.7	0.89	1.75	0.86	1.72	0.78	1.75	0.84	1.83	0.78	1.82	0.59
Memorial Symptoms Assessment Scale (psychological symptom subscale)
I & II	1.21	0.76	1.16	0.74	1.05	0.81	0.99	0.81	1	0.77	1.03	0.84	0.059	0.766
III	1.27	0.77	1.25	0.72	1.15	0.78	1.15	0.78	1.19	0.87	1.01	0.83
Total	1.24	0.76	1.2	0.73	1.1	0.8	1.07	0.8	1.09	0.82	1.02	0.83
Memorial Symptoms Assessment Scale (total number of symptoms)
I & II	10.57	5.5	10.26	4.83	9.48	5.14	8.22	4.43	7.22	4.24	6.59	3.98	<0.001	0.345
III	11.47	5.24	11.80	6.47	11.18	5.59	9.88	5.45	7.22	4.91	6.55	5.50
Total	11	5.37	10.99	5.7	10.29	5.4	9.01	4.98	7.22	4.55	6.57	4.74
Quality of life
Functional Assessment of Cancer Therapy—lung(total score)
I & II	100.97	18.81	98.48	18.49	100.87	20.51	98.73	21.11	101.21	21.37	103	19.85	0.52	0.703
III	98.04	19.68	94.21	21.93	92.96	23.99	95.63	23.1	94.32	20.92	95.98	19.81
Total	99.72	19.12	96.65	20.01	97.49	22.27	97.41	21.89	98.27	21.33	100	20.02
Functional Assessment of Cancer Therapy - physical well-being
I & II	22.71	6.18	21.42	6.38	21.29	7.9	21.82	5.90	23.86	5.05	24.16	4.04	<0.001	0.823
III	22.42	5.97	19.56	7.68	19.92	6.83	20.14	6.11	21.83	5.11	22.57	4.94
Total	22.58	6.05	20.58	7.02	20.67	7.43	21.06	6.02	22.94	5.15	23.44	4.52
Functional Assessment of Cancer The rapy—socia1/family well-being
I & II	19.75	5.97	20.01	7.06	20.04	6.7	18.06	7.8	18.31	8.79	18.07	9.29	0.016	0.863
III	20.14	7.04	20.77	6.83	20.16	7.23	19.52	8.19	19.35	7.89	18.14	8.57
Total	19.93	6.45	20.35	6.93	20.09	6.91	18.72	7.98	18.78	8.37	18.1	8.92
Functional Assessment of Cancer Therapy—emotional well-being
I & II	18.51	4.46	18.42	4.14	18.51	5	19.14	5.36	19.03	6.09	19.29	5.70	0.532	0.195
III	17.93	5.16	18.32	4.56	16.98	5.44	17.60	5.5	15.84	5.83	17.19	6.95
Total	18.25	4.77	18.37	4.32	17.82	5.24	18.44	5.45	17.58	6.15	18.34	6.35
Functional Assessment of Cancer Therapy—functional well-being
I & II	15.04	4.62	14.64	5.26	14.73	4.99	14.72	5.41	14.59	4.88	14.19	4.99	0.092	0.731
III	15.23	5.13	14	5.04	14.6	4.72	14.39	4.63	13.73	4.08	12.94	5.52
Total	15.12	4.84	14.35	5.14	14.67	4.85	14.57	5.05	14.2	4.53	13.62	5.25
Functional Assessment of Cancer Therapy—lung cancer subscale
I & II	23.8	5.87	23.22	5.07	23.6	5.25	23.68	4.86	24.48	4.78	24.65	5.07	0.143	0.476
III	24.21	4.96	22.27	5.5	22.51	5.8	23.37	5.87	23.46	4.94	22.93	5.19
Total	23.99	5.46	22.79	5.26	23.11	5.5	23.54	5.31	24.02	4.85	23.87	5.17
Functional Assessment of Chronic illness Therapy-spirituality subscale tota.1 score
I & II	35.08	7.73	32.31	7.76	33.46	9.16	33.35	9.74	32.35	8.84	32.49	9.88	0.059	0.623
III	34.23	9.06	33.79	8.05	34.01	9.5	33.07	9.61	33.03	8.78	31.91	11.29
Total	34.69	8.33	32.98	7.89	33.71	9.27	33.23	9.63	32.66	8.78	32.23	10.5
Functional Assessment of Chronic illness Therapy-spirituality subscale meaning
I & II	25.21	4.84	23.63	5.45	24.18	5.77	24.24	6.35	23.81	5.35	24.29	6.3	0.057	0.233
III	24.98	5.52	24.55	4.92	24.23	6.24	24.1	6.31	23.53	5.29	22.36	7.17
Total	25.1	5.14	24.04	5.21	24.2	5.95	24.17	6.3	23.68	5.29	23.41	6.74
Functional Assessment of Chronic illness Therapy-spirituality subscale faith
I & II	9.87	5	8.64	4.95	9.28	5.57	9.11	5.93	8.37	5.76	8.22	6.05	0.262	0.379
III	9.25	5.29	9.3	5.21	9.78	5.34	8.97	4.77	9.26	5.26	9.2	6.34
Total	9.59	5.12	8.94	5.05	9.51	5.54	9.05	5.4	8.78	5.53	8.67	6.17