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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: J Bone Miner Res. 2013 Jun;28(6):1468–1477. doi: 10.1002/jbmr.1867

Fig. 2.

Fig. 2

Contribution of DAG lipase or InsP3 Receptors to the basal or Cx43-potentiated FGF2 response of a Runx2 reporter. Luciferase reporter assays were performed on cells co-transfected with p6xOSE2-Luc and pSFFV-neo empty vector (grey bars) or pSFFV-Cx43 expression vector (black bars) and treated with vehicle (Veh) or FGF2 (10ng/ml, 4h) in the presence or absence of (A) the DAG lipase inhibitor RHC-80267 (20μM) or (B) the InsP3 Receptor inhibitor 2-APB (50μM). Graphs depict means + s.d. for a representative experiment performed in triplicate wells, n = 3. * p-value < 0.05 relative to the corresponding FGF2-treated control.