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Inhibition of IP6Ks reduces the expression of Runx2-regulated osteoblast genes. MC3T3 cells were treated with vehicle (DMSO) or 5μM TNP for 4 hours, prior to isolation of RNA for quantitative real time RT-PCR for collagen Iα1 (Col1a1), osteocalcin, Osterix or Runx2. * p-value < 0.05 relative to the corresponding Veh-treated control, n = 3.
