Figure 1.

Both trophoblasts and DSCs express CCR3, whereas only trophoblasts secrete CCL24 in human early pregnancy. A. The expression of CCL24 and its receptor CCR3 in villi and decidua was analyzed by immunohistochemistry. Red arrow: DSCs. Red triangle: blood vessel. Red star: epithelial gland. Black arrow: trophoblasts. Original magnification: ×200. The secretion of CCL24 (B) by primary trophoblasts and DSCs were determined by ELISA, and the expression of CCR3 on DSCs (C) by flow cytometry. Tro: trophoblast cells. DSC: decidual stromal cells. Error bars depict the standard deviation of the mean. **P<0.01 compared to the secretion level of 24 h.