Table 2.
Prevalence of mutations in the core promoter region between HCC and CH patients infected with HBV/C1
| Mutation | Total (n=207) | HCC (n=102) | CH (n=105) | P value | OR (95% CI) |
|---|---|---|---|---|---|
| T1653 | 27 (13.0%) | 18 (17.6%) | 9 (8.5%) | 0.103 | … |
| V1753 | 43 (29.5%) | 43 (42.1%)* | 18 (17.1%) | 0.034 | 3.071 (1.68–5.86) |
| T1762/A1764 | 135 (65.2%) | 77 (75.5%) | 58 (55.1%) | 0.843 | … |
| T1766 | 26 (25.5%) | 19 (18.6%)* | 7 (6.7%) | 0.044 | 2.146 (0.96–7.12) |
| A1768 | 35 (16.9%) | 26 (24.5%)* | 9 (8.6%) | 0.021 | 2.869 (1.21–6.49) |
HCC, hepatocellular carcinoma; CH, chronic heptitis; OR, odds ratio; CI, confidence interval.
*
P<0.05 comparing the frequency of triple mutation or quadruple mutation in HCC vs. CH.