Table 2.
Genotypes and allele frequencies in the patient and control groups
| SNP | Genotype | MDD patients n=114 (%) | Healthy volunteers n=224 (%) | Hardy-Weinberg Equilibrium analysis | |
|---|---|---|---|---|---|
|
| |||||
| X2 | p | ||||
| rs1799732 (-141delc) | C/C | 98 (86.0) | 178 (79.5) | 3.1 | 0.09 |
| C/- | 12 (10.5) | 34 (15.2) | |||
| -/- | 4 (3.5) | 12 (5.3) | |||
| Allele: C | (91.2) | (87.1) | |||
| Allele: -/ | (8.8) | (12.9) | |||
| rs6277 (C957T) | CC | 102 (89.5) | 196 (88.3) | 1.6 | 0.20 |
| CT | 10 (8.8) | 24 (10.8) | |||
| TT | 2 (1.7) | 2 (0.9) | |||
| Allele: C | (93.9) | (93.7) | |||
| Allele: T | (6.1) | (6.3) | |||
| rs1800497 (Taq1A) | CC | 14 (12.2) | 28 (12.5) | 1.5 | 0.20 |
| CT | 50 (43.9) | 114 (50.9) | |||
| TT | 50 (43.9) | 82 (36.6) | |||
| Allele: C | (34.0) | (38.0) | |||
| Allele: T | (66.0) | (62.0) | |||
Abbreviations: MDD, Major Depressive Disorder; n, Number; (%), Percentage; Hardy-Weinberg Equilibrium analysis: P>0.05, suggested that all samples were in agreement with Hardy-Weinberg equilibrium.