Table 1. Number of viral copies in tissues after AAV vector administration to mouse submandibular glands.

Tissue	AAVhEPO	Control
Salivary glands	13,185	480
Spleen	336	303
Liver	567	511
Testis	183	204

AAVhEPO (10⁹ particles per animal suspended in 50 μl of 0.9% NaCl) was delivered to mouse submandibular glands by means of intraductal cannulation. Control (naïve) animals were administered 50 μl of 0.9% NaCl via the same route. After 8 weeks, animals (n = 4 per group) were killed, the indicated tissues were obtained, and DNA was extracted, as described in Materials and Methods. Viral copy number was determined by QPCR as described in Materials and Methods.