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Zymogram analysis of MMP-2 activity in RPE-choroid, reported as percentage increase with respect to untreated wt mice. Eyecups homogenates of apoE−/− mice showed an increase in gelatinase activity in comparison to WT-C mice. Mutivitamin treatment (AE-MV50) reduced MMP-2 activity back to control levels. AE-LUT and AE-MV15 groups exhibited a little but no significant reduction. Differences from WT-C are marked as **P < 0.01 and from AE-C as †† P < 0.01 (n = 6-7).
