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. Author manuscript; available in PMC: 2013 May 19.
Published in final edited form as: Crit Care Med. 2011 Dec;39(12):2711–2721. doi: 10.1097/CCM.0b013e3182284a5f

Figure 6. SOD inhibitor DECT relieves protective effect of amifostine against HTV-induced lung injury and blocking of HTV-induced stress signaling.

Figure 6

Mice were preconditioned with amifostine (25 mg/kg, three daily injections) with or without DETC injection prior to HTV. Control animals were treated with vehicle (PBS). A - Measurements of cell counts and protein content in BAL samples. Values are mean ± SD, n=4 for each group; ***p<0.001. B - Phosphorylation of p38 MAP kinase and degradation of IκBα was analyzed by western blot and quantified by densitometry. Results of densitometry shown as mean±SD; n=4 for each group; *p<0.05.