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Effects of AT1 and mas receptor antagonists on circulating (a), heart (b), and kidney cortex (b) renin–angiotensin–aldosterone system components. Values are expressed as mean ± SEM. n=7 per group. Abbreviations: Ang I, angiotensin I; Ang II, angiotensin II; Ang-(1–7), angiotensin-(1–7); A-779, mas receptor antagonist [D-ALA7]-Ang-(1–7); Olm, olmesartan; RAS, renin–angiotensin system. *P < 0.05 vs. control; +P < 0.05 vs. Olm; ‡P < 0.05 vs. A-779.
