Table 1.
Variables | Control | A-779 | OLM | OLM + A-779 |
---|---|---|---|---|
Body weight, g | 436±7 | 447±5 | 436±9 | 442±11 |
Left kidney weight, g | 1.46±0.01 | 1.52±0.03 | 1.48±0.02 | 1.48±0.05 |
Right kidney weight, g | 1.53±0.02 | 1.56±0.03 | 1.53±0.02 | 1.53±0.04 |
Heart weight, g | 1.35±0.02 | 1.41±0.02 | 1.03±0.04* | 1.01±0.02*,‡ |
Heart weight/body weight ratio, mg/kg | 3.09±0.05 | 3.16±0.04 | 2.37±0.10* | 2.29±0.05*,‡ |
Values are means ± SEM. A-779, mas receptor antagonist [D-ALA7]-Ang-(1–7). Abbreviation: OLM, olmesartan.
*P < 0.05 vs. control; ‡P < 0.05 vs. A-779.