Table 2.
Enzyme | Control | A-779 | OLM | OLM + A-779 |
---|---|---|---|---|
ACE, nmol/mg/min | 1.9±0.6 | 2.5±0.3 | 2.4±0.9 | 2.0±0.8 |
ACE2, fmol/mg/min | 32.0±1.7 | 30.6±1.0 | 36.7±1.7 | 34.4±1.9 |
NEP, fmol/mg/min | 95.5±2.9 | 105.0±4.1 | 100.9±4.7 | 97.5±4.3 |
Values are mean ± SEM. A-779, mas receptor antagonist [D-ALA7]-Ang-(1–7). Abbreviation: OLM, olmesartan.