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. Author manuscript; available in PMC: 2013 May 19.
Published in final edited form as: J Neurochem. 2008 Jul 31;107(1):253–264. doi: 10.1111/j.1471-4159.2008.05601.x

Figure 2.

Figure 2

(A) Western blots of total protein extracts from brain and spinal cord confirm the absence of the 68kDa Gan protein in knockout mice. However a 47.5 kDa band was detected in spinal cord extract and enriched in the GanΔex1;Δex1 mice. (B) RT-PCR analyses of total RNA from liver, brain and spinal cord show that a Gan mRNA species is still present in the spinal cord but not in the brain of GanΔex1;Δex1 (arrow). (C) Schematic representations of GAN gene and Gan mRNA species. (D) Comparison of Gan and sGig mRNAs. (E) Predicted Gan and sGig proteins.