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. Author manuscript; available in PMC: 2013 May 19.
Published in final edited form as: Cloning Stem Cells. 2007 Winter;9(4):549–563. doi: 10.1089/clo.2007.0032

Figure 7. Long-term follow-up of transplanted beating embryoid bodies reveals teratoma formation.

Figure 7

(a) Representative bioluminescence imaging shows teratoma formation in both the Bi-Tet (−Dox) and Bi-Tet (+Dox) animals. (b) Representative postmortem histology of the explanted hearts shows (i) apoptosis of some transplanted cells in the BiTet (−Dox) group as well as differentiation into (ii) glandular epithelia (endoderm), (iii) cartilage (mesoderm), and (iv) squamous epithelia (ectoderm) in the heart.