Table 2.
CTRL | ETOH | P | |
---|---|---|---|
Lipid droplet protein mRNA expression | |||
Plin1 | 0.03 ± 0.01 | 0.02 ± 0.01 | 0.26 |
Plin2 | 112.0 ± 13.2 | 201.0 ± 21.2 | 0.002 |
Plin3 | 9.39 ± 1.0 | 9.58 ± 0.9 | 0.89 |
Hepatic ceramides (pmole/sample) | |||
C14 | 1.40 ± 0.3 | 1.54 ± 0.3 | 0.72 |
C16 | 21.24 ± 2.8 | 18.96 ± 2.2 | 0.54 |
C18 | 3.90 ± 0.6 | 8.42 ± 1.1 | 0.006 |
C18:1 | 0.56 ± 0.1 | 0.90 ± 0.1 | 0.02 |
C20 | 25.04 ± 3.3 | 33.74 ± 3.3 | 0.10 |
C20:1 | 1.84 ± 0.1 | 2.42 ± 0.3 | 0.06 |
C22 | 33.42 ± 1.6 | 38.78 ± 2.7 | 0.13 |
C22:1 | 10.12 ± 0.5 | 13.16 ± 0.9 | 0.02 |
C24 | 30.10 ± 1.8 | 35.22 ± 2.4 | 0.12 |
C24:1 | 54.94 ± 3.0 | 74.46 ± 2.6 | 0.001 |
C26 | 0.12 ± 0.02 | 0.1 ± 0 | 0.35 |
C26:1 | 0.08 ± 0.04 | 0.16 ± 0.02 | 0.11 |
CTRL= control-fed mice; ETOH= ethanol-fed mice; Plin1= Perilipin 1; Plin2= Perilipin 2; Plin3= Perilipin 3. Expression of Plin1, 2 and 3 was normalized to 36B4 (phosphoriboprotein).