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Representative individual subject fits of model equations to observed plasma hemoglobin (□), total clearance (○), erythropoietin (χ), and EPOR fraction (△). Hb values were obtained from the Hb mass balance fit (Eq.9-14). EPO values were obtained experimentally using RIA. Total clearance and EPOR fraction are obtained from 125I-rhEPO disposition model (Eq.1-8).
