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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Magn Reson Med. 2013 Feb 7;70(6):10.1002/mrm.24597. doi: 10.1002/mrm.24597

Figure 5. Volumetric analysis of Gbx2-CKO cerebellum and midbrain subregions.

Figure 5

Semi-automated ROI analysis showed significant differences in the whole brain, and a number of sub-regions at developmental stages between P3 and P11 (mean ± standard deviation shown in each region for Gbx2-CKO and wildtype (WT) littermates, N=6 for each genotype and stage). (a) The Gbx2-CKO mouse brain was significantly smaller than WT at each stage. After normalization to the whole brain volume, there were also stage-dependent differences in the volumes of the: (b) cerebellum; (c) hemispheres; (d) vermis; (e) flocculus-paraflocculus; (f) deep cerebellar nuclei; (g) inferior colliculus (IC); and (h) superior colliculus (SC). The p-values for each statistical comparison (WT vs Gbx2-CKO) were denoted as follows: *p < 0.05; **p < 0.01; ***p < 0.001.