Table 1.
Participant characteristics
| Demographic | BMI <25 n=298 | BMI 25–29.9 n=440 | BMI ≥30 n=516 | Overall n=1254 |
|---|---|---|---|---|
| Variables | Mean±SD |
|||
| Age (years) | 54.6±12.8 | 56.4±11.7 | 54.6±11.2 | 54.5±11.7 |
| Gender (%) | ||||
| Male | 31.2 | 52.7 | 42.1 | 43.20 |
| Female | 68.8 | 47.3 | 57.9 | 56.80 |
| Race (%) | ||||
| Non-Hispanic white | 94.0 | 94.0 | 90.3 | 92.60 |
| Hispanic | 0.4 | 0.8 | 0.3 | 0.05 |
| African American | 1.9 | 1.6 | 4.0 | 2.60 |
| Asian/Pacific Islander | 0.7 | 0.3 | 0.0 | 0.30 |
| Native American | 1.1 | 0.8 | 2.0 | 1.30 |
| Other | 1.9 | 2.6 | 3.5 | 2.30 |
| Medication use (%) | ||||
| Cholesterol-lowering | 13.1 | 32.3 | 32.6 | 27.80 |
| Corticosteroids | 12.8 | 12.5 | 11.4 | 12.10 |
| Antidiabetics | 4.7 | 8.4 | 15.3 | 10.40 |
| Antidepressants | 14.4 | 13.4 | 16.9 | 14.2 |
| Hormone replacement therapy | 9.4 | 8.6 | 5.0 | 7.3 |
| Oral contraceptives | 3.7 | 3.4 | 1.0 | 2.5 |
| Currently smoking | 17.8 | 14.1 | 14.0 | 14.90 |
| BMI (kg/m2) | 22.7±1.8 | 27.4±1.4 | 35.9±5.7 | 29.8±6.6 |
| IL-6 (pg/ml) | 2.4±3.1 | 2.7±2.48 | 3.7±3.2 | 3.0±3.1 |
| IL-6sr (pg/ml) | 34473.1±10861.9 | 35337.4±10065.1 | 35475.7±10325.7 | 35184.7±10359.1 |
| CRP (μg/ml) | 1.5±2.5 | 2.5±4.0 | 4.4±5.9 | 3.0±4.8 |
| Fibrinogen (mg/dl) | 315.8±75.9 | 343.2±82.1 | 373±92.1 | 348.9±87.9 |
| sE-Selectin (ng/ml) | 36.9±19.6 | 41.2±20.6 | 49.1±24.7 | 43.4±22.7 |
| sICAM-1 (ng/ml) | 284.8±122.0 | 276.2±99.9 | 301.4±123.1 | 288.6±115.6 |
BMI, body mass index; IL, interleukin; IL-6sr, IL-6 soluble receptor; MMW, MET-minutes per week; sE-selectin, soluble E-selectin; sICAM-1, soluble intracellular adhesion molecule-1.