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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Pharmacol Biochem Behav. 2013 Jan 16;104:177–187. doi: 10.1016/j.pbb.2013.01.005

Fig. 7.

Fig. 7

Binge drinking using DID-MSA significantly alters locomotor response to ethanol for female mice that binged during adulthood. A) During the first 5 min following injection, adult B6 females, regardless of binge drinking history, display greater locomotor response to the 1.75 g/kg ethanol challenge compared to all other groups (p<0.001). B) During the final 5 min of the ten minute test, adult females with a history of DID-MSA ethanol consumption showed a significantly greater locomotor response to this ethanol challenge, as compared to their water consuming controls (p<0.01). This effect was not noted for males or females that binged as adolescents (n=6–7/age/sex for water and n=15–16/age/ sex for ethanol).