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Magnetic resonance imaging (MRI) scans from APPdup patients. (A) Proband 1 showing extensive white matter abnormalities, microbleeds, (Aii) and an amygdala hemorrhage (Ai, arrow), and (B) proband 2 (aged 47) showing white matter abnormalities on T2 weighted scans (Bii) and hippocampal atrophy (Bi).
