Table 1.
Compound | X | HDAC1 IC50 (nM) | HDAC6 IC50 (nM) | HDAC8 IC50 (nM) |
---|---|---|---|---|
| ||||
O | NI† | NI | NI | |
S | NI | 681 ± 110 | 3675 ± 1201 |
Activities determined by SAMDI analysis
No significant Inhibition (below 20% Inhibition) at maximum tested concentration of 10 μM