c-Jun(A266S) activates the EBV lytic cycle in a cell line derived from BL. HH514-16 cells were nucleofected with plasmids encoding wt ZEBRA, Rta, wt Jun, or the basic domain mutants c-Jun(A266S) or c-Fos(A151S). The cells were assessed for expression of BRLF1 and BZLF1 mRNAs (A) and BMRF1, BaRF1, and BFRF3 mRNAs (B).