Fig.

Effect of ginseng and banaba leaf extract (GE and BLE) on accelerated mesengial expansion in fluoride toxicated STZ diabetic mice. Paraffin embedded sections of renal cortex were stained with hematoxilin and eosin (H&E). Representative light micrographs (400 X) from each mice groups are shown. (A) Control group (showing normal glomerulus; (B) STZ diabetic control; (C) Fluoride (F) toxicated control; (D) F plus STZ control; (E) G E treated F plus STZ group; (F) BLE treated F plus STZ group; (G) GE and BLE F plus group. Mesangial expansion and thickened GBMs are seen in (B) and (D) (in stright arrows) and lesions/nodules of glomeruli in (B) and (D) (in spiral arrows). Reduction in acelerated mesangial expansions seen in (E), (F) and (G).