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. Author manuscript; available in PMC: 2013 May 20.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Jan 17;33(3):474–480. doi: 10.1161/ATVBAHA.112.301078

Figure 3.

Figure 3

Effect of adeno-associated virus (AAV) 2/8 gene transfer on plasma lipid and apolipoprotein (apo) A-V content. Apoa5 (−/−) mice (8 mice per group) were transduced with AAV2/8-apoA-V or AAV2/8-LacZ (1×1012 vg each). A, α-apoA-V immunoblot of recombinant apoA-V standard (left) and pooled plasma samples from AAV2/8-apoA-V–transduced mice obtained each week for 8 weeks. B, Triacylglycerol content in plasma from 8 AAV2/8-LacZ–transduced animals (filled bars) and 8 AAV2/8-apoA-V–transduced animals (open bars). C, Cholesterol content in plasma from AAV2/8-LacZ–transduced animals (filled bars) and AAV2/8-apoA-V–transduced animals (open bars). Values reported as percent change vs week 0 values as mean±SEM (n=8).