. Author manuscript; available in PMC: 2014 Jan 1.

Published in final edited form as: J Thorac Cardiovasc Surg. 2012 Oct 27;145(1):196–205. doi: 10.1016/j.jtcvs.2012.09.057

TABLE 4.

Results of the mixed-effect model using time after removal from cardiopulmonary bypass and deep hypothermic circulatory arrest duration (for single-ventricle patients) or total support time (for 2-ventricle patients) as predictors for outcome measurements

CHD type	Outcome variable	Model predictor	Estimate (SE) of coefficient	P value
One ventricle	rCMRO₂	Time, h	0.022 (0.025)	.42
		DHCA, min	0.007 (0.009)	.45
	rOEF	Time, h	−0.003 (0.015)	.84
		DHCA, min	−0.0002 (0.005)	.96
	rCBF	Time, h	0.003 (0.021)	.87
		DHCA, min	0.001 (0.007)	.87
	rCaO₂	Time, h	0.031 (0.006)	<.0001
		DHCA, min	−0.009 (0.002)	.0001
Two ventricles	rCMRO₂	Time, h	0.045 (0.030)	.16
		TST, min	0.003 (0.003)	.29
	rOEF	Time, h	−0.014 (0.014)	.31
		TST, min	0.003 (0.001)	.008
	rCBF	Time, h	0.046 (0.019)	.027
		TST, min	−0.001 (0.002)	.47
	rCaO₂	Time, h	0.011 (0.009)	.26
		TST, min	0.0003 (0.0007)	.73

Logarithm transformations were used on all outcome variables to make the data more normally distributed. Coefficient estimates are reported along with SE. CHD, Congenital heart defect; SE, standard error; rCMRO₂, relative change in the cerebral metabolic rate of oxygen; DHCA, deep hypothermic circulatory arrest; rOEF, relative change in postoperative oxygen extraction fraction; rCBF, relative change in postoperative cerebral blood flow; rCaO₂, relative change in postoperative arterial oxygen concentration; TST, total support time.