Table II.
TSH (uIU/mL) | |||||
---|---|---|---|---|---|
Variables | All | Over-dosed (<0.45) | Euthyroid (0.45–4.5) | Under-dosed (>4.5) | p value |
n (%) | 122 | 51 (41.80%) | 39 (31.96%) | 32 (26.23%) | |
Age, years | 49.0 ± 1.2 | 51.3 ± 1.8 | 48.8 ± 2.2 | 45.5 ± 2.6 | p=0.19 |
BMI, kg/m2 | 30.5 ± 0.8 | 32.3 ± 1.5 | 31.0 ± 1.2 | 27.0 ± 1.5 | p=0.030 |
Initial dose of LT4, mcg/kg/day | 1.58 ± 0.02 | 1.61 ± 0.03 | 1.58 ± 0.05 | 1.53 ± 0.03 | p=0.34 |
Eventual Euthyroid dose of LT4, mcg/kg/day | 1.61 ± 0.03 | 1.46 ± 0.03 | 1.58 ± 0.05 | 1.89 ± 0.07 | p<.0001 |
TSH= Thyroid Stimulating Hormone
BMI= body mass index calculated as weight in kilograms divided by the square of the height in meters
LT4= levothyroxine
Data are represented as the mean +/− SEM
Differences among groups analyzed with ANOVA