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. Author manuscript; available in PMC: 2014 Apr 10.
Published in final edited form as: J Am Chem Soc. 2013 Apr 2;135(14):5364–5367. doi: 10.1021/ja402274g

Table 1.

Optimization of Reaction Conditions

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entrya base solvent yield (%)b
1 CsOPiv (200 mol %) MeOH (0.5 M) 24
2 CsOPiv (200 mol %) EtOH (0.5 M) 33
3 CsOPiv (200 mol %) TFE (0.5 M) 59
4 CsOPiv (200 mol %) MeCN (0.5 M) 78
5 CsOAc (200 mol %) MeCN (0.5 M) 80
6 CsOAc (20 mol %) MeCN (0.1 M) 81c
7 - MeCN (0.1 M) 0
8d CsOAc (20 mol %) MeCN (0.1 M) 75c
a

Standard Conditions: 1a (1 equiv), 2a (1 equiv), [RhCp*Cl2]2 (1 mol %).

b

Yield determined by HPLC.

c

Isolated Yield.

d

Catalyst loading (0.4 mol %)