Figure 6.

Pre-existing antibodies to HA peptides that correlate with expression of apoptosis module. Individuals were sorted and divided by expression levels of genes in the APO module (A) and reactivity to HA peptides was compared between individuals with high or low gene expression (B). Various HA peptides’ reactivities were significantly different between the APO high and low groups. Peptides H1_1, H1_6, H1_16, H3_15, H3_21, BH21 and BH23 (asterisks) were found to be predictive of the HAI titer in response to the vaccine. Red circles=young, Green circles=older.