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. 2013 Jan 30;2013:184360. doi: 10.1155/2013/184360

Figure 6.

Figure 6

Total Cd accumulation measured by FAAS in CHOCα and wild-type CHO cells. Both cell types were incubated for 1 hour in medium containing 0, 50, or 100 μM Cd and other modifiers. Cd determination was normalized to the cell volume (see text). Treatments were as follows: control 0 Cd (basal), 60 min Cd (Cd), Cd + 30 mM  KCl (K), Cd + 30 mM  KCl, and 1 μM BayK (B), Cd + 30 mM  KCl and 1 μM nimodipine (N). Depolarization (treatment K) did not increase significantly the intracellular concentration of Cd (P > 0.05). In CHOCα cells, but not in wild-type CHO, BayK significantly enhanced and nimodipine significantly reduced Cd accumulation, both with P < 0.001 (*), with respect to the same treatments in depolarization. Bars represent mean ±  sem in at least 10 experiments in each group.