Figure 1.

Expression profiles of miR-125b in oral squamous cell carcinoma (OSCC)-derived cell lines and OSCC samples. The quantification of miR-125b expression levels in OSCC-derived cell lines (A) and OSCC samples (B) was performed by real-time qRT–PCR analyses. The data are expressed as means±s.d. Significantly lower miR-125b expression levels were detected in primary OSCCs compared with matched normal tissues (P=0.019, Student's t-test) (C). The data are expressed as means±s.d. The overall survival rate was investigated by Kaplan–Meier analysis (D). Lower miR-125b expression levels were significantly associated with poor outcome in patients with OSCC. The log-rank test revealed significant P-values (P=0.038).