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. 2013 Mar 20;31(5):1003–1010. doi: 10.3892/ijmm.2013.1311

Figure 5.

Figure 5

Both the expression of PPARδ mRNA and miR-9 are higher in M1 than in M2 macrophages. The expression of miR-9 and PPARδ mRNA was measured in macrophages, after 7 days of treatment with IFN-γ or IL-4 to obtain the M1 and M2 phenotypes, respectively. The experiment was repeated 5 times using monocytes from 6 different donors. Mir-9 expression was normalized to U48 expression and PPARδ expression was normalized to 18s expression. Means ± SD of 5–6 independent experiments are shown. *P<0.05.