(A) Western blot bands for JAK2, p-JAK2, STAT3 and p-STAT3 expression in the control group, the pc-DNA3.1(+) group, the HBx 24 h group, the HBx 48 h group and the HBx 72 h group. (B) Histogram of the relative expression of JAK2, p-JAK2, STAT3 and p-STAT3 protein in the control group, the pc-DNA3.1(+) group, the HBx 24 h group, the HBx 48 h group and the HBx 72 h group. (C) Immunofluorescence showing p-STAT3 expression in the control group, the pc-DNA3.1(+) group, the HBx 24 h group, the HBx 48 h group and the HBx 72 h group. (D) Immunofluorescence showing STAT3 expression in the control group, the pc-DNA3.1(+) group, the HBx 24 h group, the HBx 48 h group and the HBx 72 h group (x400). (E) Western blot bands of JAK2, p-JAK2, STAT3 and p-STAT3 in the various groups with AG490, compared with the corresponding groups without AG490. (F) Histogram of the relative expression of JAK2, p-JAK2, STAT3 and p-STAT3 protein in the various groups with AG490, compared with the corresponding groups without AG490.