Table 2.
Pairs | ASD | Restricted/ Repetitive |
Language | Social | |
---|---|---|---|---|---|
Overall | No. discordant pairs* | 34 | 151 | 120 | 37 |
No. lighter child meeting cut-off | 26 | 92 | 80 | 26 | |
OR (95% CI) | 3.25‡ (1.47, 7.18) | 1.56‡ (1.12, 2.16) | 2.00‡ (1.37, 2.92) | 2.36† (1.17, 4.78) | |
MZ | No. discordant pairs* | 7 | 38 | 41 | 8 |
No. lighter child meeting cut-off | 5 | 23 | 30 | 6 | |
OR (95% CI) | 2.50 (0.49, 12.89) | 1.53 (0.80, 2.94) | 2.72‡ (1.37, 5.44) | 3.00 (0.61, 14.86) | |
DZ | No. discordant pairs* | 19 | 88 | 62 | 22 |
No. lighter child meeting cut-off | 14 | 54 | 41 | 15 | |
OR (95% CI) | 2.80† (1.01, 7.77) | 1.59† (1.03, 2.44) | 1.95† (1.15, 3.30) | 2.14 (0.87, 5.26) | |
Males | No. discordant pairs* | 25 | 98 | 81 | 24 |
No. lighter child meeting cut-off | 18 | 63 | 52 | 16 | |
OR (95% CI) | 2.57† (1.07, 6.16) | 1.80‡ (1.19, 2.72) | 1.79† (1.14, 2.82) | 2.00 (0.86, 4.67) | |
Females | No. discordant pairs* | 9 | 63 | 39 | 13 |
No. lighter child meeting cut-off | 8 | 29 | 28 | 10 | |
OR (95% CI) | 8.00† (1.00, 63.96) | 1.21 (0.70, 2.08) | 2.55‡ (1.27, 5.11) | 3.33 (0.92, 12.11) |
OR=Odds Ratio; CI=Confidence Interval;
Discordant for birth weight and ASD (or ASD-like traits) on the A-TAC. Birth weight discordance defined as ≥ 400 gram difference in birth weight between the twins in a pair, or one twin at least 15% lighter than the other in the pair;
p≤0.05;
p≤ 0.01.