Figure 2.

a-d 24-h ambulatory blood pressure profiles in colorectal cancer patients in response to bevacizumab infusion. Diastolic blood pressure during daytime but not during nighttime decreased after bevacizumab infusion (Figure 2a,b). The proportion of individuals with pathological blood pressure profile increased after bevacizumab (Figure 2c,d). Legend: systolic blood pressure (broken lines), diastolic blood pressure (smooth lines); proportions are based on the diagnostic criteria of the European Society of Hypertension and the American Hypertension Association before (day-1), during (day 0) and after (day+1) bevacizumab infusion.