Table 5.

Cytokine production by splenocyte^a cultures from immunized BALB/c mice

Group	Cytokine production (pg/mL)b
	IFN-γ	IL-4	IL-10
PBS	47.59 ± 4.63	37.26 ± 2.84	44.34 ± 2.77
PBudCE4.1	48.35 ± 1.86	33.70 ± 3.29	38.70 ± 2.70
pTgCPB	674.93 ± 83.36*	32.58 ± 3.72	34.60 ± 1.92
pTgCPL	585.14 ± 112.03*	32.34 ± 3.87	35.47 ± 1.94
pTgCPB/TgCPL	1182.23 ± 94.28*#	36.11 ± 3.51	34.57 ± 2.14

IFN, interferon; IL, interleukin, PBS, phosphate-buffered saline.

^a Splenocytes were obtained from 3 mice per group and were collected at week 4 after the final immunization.

^b Values for IFN-γ at 96 h. Values for IL-10 at 72 h. Values for IL-4 at 24 h.

*Compared with the PBS-adjuvant or pBudCE4.1 controls (P < 0.05); # compared with pTgCPB or pTgCPB (P < 0.05).