Figure 4. Inhibition of chlamydial development with a panel of pannexin-inhibitory drugs.
C. trachomatis infected HeLa cells were maintained with 1.5 mM probenecid (Pro), 75 µM glyburide (Gly), 75 µM carbenoxolone (Carb), 100 µM IAA, or 100 µM NPPB for 24 hr. Data for progeny counts are represented as mean ± standard deviation of duplicate samples, and One-Way ANOVA analysis was used to compare drug treatments to the mock control (*; P<0.05).